BDBM50096516 1'-[3-(3,4-dichlorophenyl)-4-methyl(8-quinolyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]::CHEMBL315084

SMILES CN(C[C@@H](CCN1CCC2(CS(=O)c3ccccc23)CC1)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1cccc2cccnc12

InChI Key InChIKey=SHRJWZUAWVEGAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096516   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096516(1'-[3-(3,4-dichlorophenyl)-4-methyl(8-quinolyl)sul...)
Affinity DataIC50: 90nMAssay Description:Binding affinity towards human CCR5 receptor in Chinese hamster ovary (CHO) cells using [125I]-MIP-1 alpha as radioligand at a concentration of 1000 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096516(1'-[3-(3,4-dichlorophenyl)-4-methyl(8-quinolyl)sul...)
Affinity DataIC50: 1.40E+4nMAssay Description:Antagonist activity at Homo sapiens (human) CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article