BDBM50096488 (1S,3R)-1-(Naphthalene-2-sulfonyl)-4-(3-piperidin-1-yl-propionyl)-3-propyl-hexahydro-pyrrolo[3,2-b]pyrrol-2-one; hydrochloride::CHEMBL2368613

SMILES [H][C@]12CCN(C(=O)CCN3CCCCC3)[C@]1([H])[C@@H](CCC)C(=O)N2S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=YUAGXXDKPAMZTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096488   

TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50096488((1S,3R)-1-(Naphthalene-2-sulfonyl)-4-(3-piperidin-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50096488((1S,3R)-1-(Naphthalene-2-sulfonyl)-4-(3-piperidin-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed