BDBM50096472 2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-3-(2-(hydroxyamino)-2-oxoethoxy)benzamide::2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-3-hydroxycarbamoylmethoxy-benzamide::CHEMBL80272

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OCC(=O)NO)cccc1C(=O)NO

InChI Key InChIKey=CBMKHOZXSARYNG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50096472   

LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50: 81nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed