BDBM50096334 CHEMBL3577122

SMILES Cc1cc(F)c(NC(=O)NCCC(C)(C)C)cc1-c1cc2cnc(N)nc2nc1C

InChI Key InChIKey=VEIJBVGMVKSNDC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096334   

TargetSerine/threonine-protein kinase B-raf(Human)
Eli Lilly

Curated by ChEMBL

LigandBDBM50096334(CHEMBL3577122)Copy SMILESCopy InChI

Affinity DataIC50: 7.90nMAssay Description:Inhibition of recombinant BRAF V600E mutant (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/18/2016
Entry Details Article
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TargetVascular endothelial growth factor receptor 2(Human)
Eli Lilly

Curated by ChEMBL

LigandBDBM50096334(CHEMBL3577122)Copy SMILESCopy InChI

Affinity DataIC50: 540nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/18/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL