BDBM50096152 CHEMBL3593996

SMILES COc1cc(ccc1NC(=O)C1CC1)-c1ccc(-c2nc3c(cc(F)cc3[nH]2)C(N)=O)c(F)c1

InChI Key InChIKey=CBCSBULXSUNMKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096152   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Malaya

Curated by ChEMBL
LigandPNGBDBM50096152(CHEMBL3593996)
Affinity DataIC50: 980nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein after 60 mins by TACS-Sapphire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Malaya

Curated by ChEMBL
LigandPNGBDBM50096152(CHEMBL3593996)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of DHODH (unknown origin) using L-DHO, DUQ, DCIP as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed