BDBM50095961 CHEMBL3593768

SMILES NC(=O)c1cnc2[nH]ccc2c1NC1CCN(CC1)C(=O)CC#N

InChI Key InChIKey=VJNOBOCHRMUKAC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095961   

TargetTyrosine-protein kinase JAK2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50095961(CHEMBL3593768)
Affinity DataIC50: 200nMAssay Description:Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50095961(CHEMBL3593768)
Affinity DataIC50: 110nMAssay Description:Inhibition of human JAK1 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50095961(CHEMBL3593768)
Affinity DataIC50: 46nMAssay Description:Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed