BDBM50095701 3-But-3-ynyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL146076

SMILES CC1C2Cc3ccc(O)cc3[C@@]1(C)CCN2CCC#C

InChI Key InChIKey=ZGMIZUFIKMQITG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095701   

TargetSigma non-opioid intracellular receptor 1(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50095701(3-But-3-ynyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2...)
Affinity DataKi:  110nMAssay Description:Ki value determined against Sigma opioid receptor type 1 using [(+)-[3H]pentazocine at the Kd concentration 2 nM. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50095701(3-But-3-ynyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2...)
Affinity DataKi:  1.50E+4nMAssay Description:Ki value determined against Sigma opioid receptor type 2 using [3H]DTG(5 nM) with 1uM dextrallorphan to mask sigma1 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed