BDBM50095612 CHEMBL3590525::US9598381, 5

SMILES Clc1ccc(CCNCCC(=O)N(CCNCCCN2CCCCC2)C2CCCCC2)cc1Cl

InChI Key InChIKey=ACRRBPSGPZFHQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095612   

TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095612(CHEMBL3590525 | US9598381, 5)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095612(CHEMBL3590525 | US9598381, 5)
Affinity DataIC50: 1.12E+4nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent