BDBM50095568 1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propionylamino)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL356520

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)NC(=O)[C@H](C)O

InChI Key InChIKey=SBIQGLZKCCTUIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095568   

TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095568(1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095568(1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -3 (stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095568(1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...)
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloprotease-13 (collagenase-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095568(1-(4-Butoxy-benzenesulfonyl)-4-(2-hydroxy-propiony...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -1 (collagenase-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed