BDBM50095556 1-(4-Methoxy-benzenesulfonyl)-4-(4-methoxy-benzenesulfonylamino)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL147910

SMILES COc1ccc(cc1)S(=O)(=O)N[C@H]1C[C@@H](N(C1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=LKSVLIAQUIGTTF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50095556   

TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095556(1-(4-Methoxy-benzenesulfonyl)-4-(4-methoxy-benzene...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095556(1-(4-Methoxy-benzenesulfonyl)-4-(4-methoxy-benzene...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloprotease-13 (collagenase-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095556(1-(4-Methoxy-benzenesulfonyl)-4-(4-methoxy-benzene...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -1 (collagenase-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095556(1-(4-Methoxy-benzenesulfonyl)-4-(4-methoxy-benzene...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -2 (gelatinase-A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095556(1-(4-Methoxy-benzenesulfonyl)-4-(4-methoxy-benzene...)
Affinity DataIC50: 36nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -3 (stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed