BDBM50095549 4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-methoxy-ethoxy)-benzenesulfonyl]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL147494

SMILES CCCn1cc(O)n([C@H]2C[C@@H](N(C2)S(=O)(=O)c2ccc(OCCOC)cc2)C(=O)NO)c1=O

InChI Key InChIKey=PILJHIOYYOZKRU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095549   

Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -2 (gelatinase-A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloprotease-13 (collagenase-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -3 (stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease -1 (collagenase-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095549(4-(2,5-Dioxo-3-propyl-imidazolidin-1-yl)-1-[4-(2-m...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed