BDBM50095515 4-[3-(2-Fluoro-benzyl)-phenyl]-2,4-dioxo-butyric acid::CHEMBL145280::CHEMBL85802

SMILES OC(=O)C(=O)CC(=O)c1cccc(Cc2ccccc2F)c1

InChI Key InChIKey=LORKTBWHCFDMKQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095515   

TargetIntegrase(Human immunodeficiency virus type 1)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095515(CHEMBL85802 | CHEMBL145280 | 4-[3-(2-Fluoro-benzyl...)
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV-1 integrase catalytic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095515(CHEMBL85802 | CHEMBL145280 | 4-[3-(2-Fluoro-benzyl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Evaluated for inhibition of HIV-1 integrase catalytic activity in terms of inhibition of 3'-processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50095515(CHEMBL85802 | CHEMBL145280 | 4-[3-(2-Fluoro-benzyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HIV-1 Integrase in strand transfer enzyme assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50095515(CHEMBL85802 | CHEMBL145280 | 4-[3-(2-Fluoro-benzyl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed