BDBM50095511 4-(2-Benzyl-thiophen-3-yl)-2,4-dioxo-butyric acid::CHEMBL197638::CHEMBL359212

SMILES OC(=O)C(=O)CC(=O)c1ccsc1Cc1ccccc1

InChI Key InChIKey=HTGWIZWPKBPISH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095511   

TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50095511(CHEMBL359212 | CHEMBL197638 | 4-(2-Benzyl-thiophen...)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant HIV-1 Integrase in strand transfer enzyme assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50095511(CHEMBL359212 | CHEMBL197638 | 4-(2-Benzyl-thiophen...)
Affinity DataIC50: 180nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed