BDBM50095403 1-(5-tert-butyl-2-(methylcarbamoyl)thiophen-3-yl)-3-p-tolylurea::5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid methylamide::CHEMBL18754

SMILES CNC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C

InChI Key InChIKey=DMHPPEKTDQSHDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095403   

TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095403(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50: 34nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095403(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095403(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed