BDBM50095399 5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carboxylic acid methyl ester::CHEMBL279377::methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2-carboxylate

SMILES COC(=O)c1sc(cc1NC(=O)Nc1ccc(C)cc1)C(C)(C)C

InChI Key InChIKey=HXUFSIDDYWPGJO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095399   

TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 413nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Raf-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 248nMAssay Description:Inhibition of p38 alpha-2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(methyl 5-tert-butyl-3-(3-p-tolylureido)thiophene-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed