BDBM50095371 5-(3-Chloro-phenyl)-7-(4-dimethylamino-phenyl)-pyrido[2,3-d]pyrimidin-4-ylamine::CHEMBL170969

SMILES CN(C)c1ccc(cc1)-c1cc(-c2cccc(Cl)c2)c2c(N)ncnc2n1

InChI Key InChIKey=OYPZCAFJCBIESQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095371   

TargetAdenosine kinase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50095371(5-(3-Chloro-phenyl)-7-(4-dimethylamino-phenyl)-pyr...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against intact cell adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine kinase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50095371(5-(3-Chloro-phenyl)-7-(4-dimethylamino-phenyl)-pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against cytosolic adenosine kinase by ADO phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed