BDBM50095296 CHEMBL3589082::US9278953, 1

SMILES CCn1ncc2c(F)cc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCCNC1=O

InChI Key InChIKey=BUSKMSQAPVYQAP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095296   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM50095296(CHEMBL3589082 | US9278953, 1)
Affinity DataKi:  2nM ΔG°:  -11.9kcal/molepH: 7.4 T: 2°CAssay Description:Test compounds were half log serially diluted in 100% DMSO (J. T. Baker #922401). 1 uL of each compound was added to appropriate wells of a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM50095296(CHEMBL3589082 | US9278953, 1)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor by MicroBeta plate-based scintillation counting/SPA binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed