BDBM50095294 CHEMBL3589084::US9278953, 7

SMILES Cn1cnc2cc(cc(Cl)c12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCCNC1=O

InChI Key InChIKey=ZCGUCJKPIMLSFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095294   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM50095294(CHEMBL3589084 | US9278953, 7)
Affinity DataKi:  7.80nM ΔG°:  -11.1kcal/molepH: 7.4 T: 2°CAssay Description:Test compounds were half log serially diluted in 100% DMSO (J. T. Baker #922401). 1 uL of each compound was added to appropriate wells of a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM50095294(CHEMBL3589084 | US9278953, 7)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor by MicroBeta plate-based scintillation counting/SPA binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed