BDBM50095292 CHEMBL3085874

SMILES Nc1nc2CCC(CNC(=O)c3cc(Br)c(Br)[nH]3)Cc2s1

InChI Key InChIKey=VALBVPDTALTKAF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50095292   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095292(CHEMBL3085874)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid and biotinylated oligonucelotide incubated for 30 mins by fluorescence based DNA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetSodium channel protein type 4 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095292(CHEMBL3085874)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.4 by automated patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium channel protein type 3 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095292(CHEMBL3085874)
Affinity DataIC50: 1.80E+4nMAssay Description:Modulation of human Nav1.3 by automated patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095292(CHEMBL3085874)
Affinity DataIC50: 2.30E+4nMAssay Description:Modulation of human Nav1.7 by automated patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50095292(CHEMBL3085874)
Affinity DataIC50: 3.00E+4nMAssay Description:Modulation of human Nav1.5 by automated patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed