BDBM50095266 (3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-amine::CHEMBL63676

SMILES CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCC

InChI Key InChIKey=ZTVIFZQDIJSFNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095266   

TargetFructose-1,6-bisphosphatase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095266((3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazoli...)
Affinity DataIC50: 530nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095266((3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazoli...)
Affinity DataIC50: 3.10E+3nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095266((3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the rat liver F16BPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed