BDBM50095220 CHEMBL94324::N-Hydroxy-2-(4-phenoxy-phenylsulfamoyl)-benzamide

SMILES ONC(=O)c1ccccc1S(=O)(=O)Nc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=YOZFGFQUBUJIAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095220   

TargetCollagenase 3(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095220(N-Hydroxy-2-(4-phenoxy-phenylsulfamoyl)-benzamide ...)
Affinity DataIC50: 9.00E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095220(N-Hydroxy-2-(4-phenoxy-phenylsulfamoyl)-benzamide ...)
Affinity DataIC50: 1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095220(N-Hydroxy-2-(4-phenoxy-phenylsulfamoyl)-benzamide ...)
Affinity DataIC50: 3.50E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed