BDBM50095203 CHEMBL94751::[(S)-6-(3-Benzhydryl-6-oxo-6H-pyridazin-1-ylmethyl)-5,6,7,8-tetrahydro-naphthalen-1-yloxy]-acetic acid

SMILES OC(=O)COc1cccc2C[C@@H](Cn3nc(ccc3=O)C(c3ccccc3)c3ccccc3)CCc12

InChI Key InChIKey=FFRFCEJVGONUHG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095203   

TargetProstacyclin receptor(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50095203([(S)-6-(3-Benzhydryl-6-oxo-6H-pyridazin-1-ylmethyl...)
Affinity DataIC50: 81nMAssay Description:Agonist activity at PGI2 in human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50095203([(S)-6-(3-Benzhydryl-6-oxo-6H-pyridazin-1-ylmethyl...)
Affinity DataIC50: 81nMAssay Description:Agonist activity at PGI2 receptor in Homo sapiens (human) platelets assessed as inhibition of ADP-induced aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetProstacyclin receptor(Human)
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50095203([(S)-6-(3-Benzhydryl-6-oxo-6H-pyridazin-1-ylmethyl...)
Affinity DataKi:  94nMAssay Description:Tested for inhibition of 3[H]-iloprost binding to human IP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed