BDBM50094985 3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one::CHEMBL313527

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(O)cc1

InChI Key InChIKey=VHWZIWIGNRZWFK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50094985   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094985(3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 6.50E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094985(3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 2.50E+5nMAssay Description:In vitro inhibitory concentration of compound required to inhibit Prostaglandin G/H synthase 1 enzyme was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094985(3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 4.80E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094985(3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 2.50E+5nMAssay Description:In vitro inhibitory concentration of compound required to inhibit Prostaglandin G/H synthase 2 enzyme was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed