BDBM50094949 CHEMBL3589378

SMILES CCN1C(=S)N2CCCC2c2c1nc(-c1ccc(OC)c(O)c1)c(C#N)c2N1CCOCC1

InChI Key InChIKey=AWYJUKXNMJGCKH-UHFFFAOYSA-N

Data  5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094949   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Cairo University

Curated by ChEMBL

LigandBDBM50094949(CHEMBL3589378)Copy SMILESCopy InChI

Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of GST-tagged p110delta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Cairo University

Curated by ChEMBL

LigandBDBM50094949(CHEMBL3589378)Copy SMILESCopy InChI

Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of Glu-tagged PI3KC2beta (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Bovine)
Cairo University

Curated by ChEMBL

LigandBDBM50094949(CHEMBL3589378)Copy SMILESCopy InChI

Affinity DataIC50: 3.80nMAssay Description:Inhibition of GST-tagged bovine p110alpha expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Cairo University

Curated by ChEMBL

LigandBDBM50094949(CHEMBL3589378)Copy SMILESCopy InChI

Affinity DataIC50: 780nMAssay Description:Inhibition of GST-tagged human p110beta expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Cairo University

Curated by ChEMBL

LigandBDBM50094949(CHEMBL3589378)Copy SMILESCopy InChI

Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of His-tagged p110gamma (unknown origin) expressed in Sf9/Baculovirus system using [gamma-33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/16/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL