BDBM50094734 CHEMBL3589361

SMILES OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C1=C(C2CC(C1O2)S(=O)(=O)Oc1ccccc1O)c1ccc(O)cc1

InChI Key InChIKey=DLWHGJVATWWUTK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094734   

TargetEstrogen receptor(Human)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094734(CHEMBL3589361)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at ER-alpha (unknown origin) transfected in HEK293T cells assessed as inhibition of transcriptional activity after 24 hrs by luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094734(CHEMBL3589361)
Affinity DataKi:  121nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50094734(CHEMBL3589361)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed