BDBM50094674 CHEMBL142862::[2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimethyl-amine

SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F

InChI Key InChIKey=CTEKFOKTEGQYLO-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50094674   

Target5-hydroxytryptamine receptor 1A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  0.930nMAssay Description:EC50 for inhibition of 50 uM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataEC50:  1.81E+4nMAssay Description:Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  0.230nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT-as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  55nMAssay Description:Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  55nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 2C receptor was determined using [125I]- DOI as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  122nMAssay Description:Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094674([2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimet...)
Affinity DataKi:  122nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 2A receptor was determined using [125I]- DOI as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed