BDBM50094672 CHEMBL444612::Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine

SMILES CCN(CC)CCc1c[nH]c2cc(F)ccc12

InChI Key InChIKey=RPWUTEXLVPDNEA-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094672   

Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094672(Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine |...)
Affinity DataEC50:  3.39E+4nMAssay Description:Evaluated for the effective concentration at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094672(Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine |...)
Affinity DataEC50:  3.70E+3nMAssay Description:EC50 for inhibition of 50 uM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094672(Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine |...)
Affinity DataKi:  145nMAssay Description:Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094672(Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine |...)
Affinity DataKi:  210nMAssay Description:Evaluated for the binding constant at [125I]-DOI-labeled rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50094672(Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine |...)
Affinity DataKi:  256nMAssay Description:Evaluated for the binding constant at [3H]8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed