BDBM50094623 CHEMBL142885::Phosphoric acid mono-[3-hydroxy-5-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl] ester(IdUMP)::[5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate

SMILES C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)I)COP(=O)(O)O)O

InChI Key InChIKey=WXFYBFRZROJDLL-UHFFFAOYSA-N

Data  2 KI

PDB links: 45 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094623   

TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50094623([5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl...)
Affinity DataKi:  6.99E+3nMAssay Description:Time-independent inhibition of thymidylate synthase from FdUrd-resistant L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50094623([5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl...)
Affinity DataKi:  7.68E+3nMAssay Description:Time-independent inhibition of thymidylate synthase from parenteral L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed