BDBM50094611 CHEMBL143376::Phosphoric acid mono-[5-(5-bromo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl] ester(BrdUMP)::[5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate

SMILES C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Br)COP(=O)(O)O)O

InChI Key InChIKey=LHLHVDBXXZVYJT-UHFFFAOYSA-N

Data  2 KI

PDB links: 137 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50094611   

TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50094611(Phosphoric acid mono-[5-(5-bromo-2,4-dioxo-3,4-dih...)
Affinity DataKi:  460nMAssay Description:Time-independent inhibition of thymidylate synthase from FdUrd-resistant L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50094611(Phosphoric acid mono-[5-(5-bromo-2,4-dioxo-3,4-dih...)
Affinity DataKi:  1.50E+3nMAssay Description:Time-independent inhibition of thymidylate synthase from parenteral L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed