BDBM50094600 CHEMBL2323029

SMILES OC(=O)c1ccc2nc(-c3ccc(Cl)cc3)c(nc2c1)-c1ccc(Cl)cc1

InChI Key InChIKey=HWARRBNHGPIIKB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50094600   

TargetCatenin beta-1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50094600(CHEMBL2323029)
Affinity DataKi:  8.80E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetTranscription factor 7-like 2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50094600(CHEMBL2323029)
Affinity DataKi:  8.80E+3nMAssay Description:Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCatenin beta-1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50094600(CHEMBL2323029)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed
TargetTranscription factor 7-like 2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50094600(CHEMBL2323029)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed