BDBM50094555 5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole::CHEMBL343311

SMILES CC1=C(C)Cc2c(C1)c([nH]c2-c1ccccc1)-c1ccccc1

InChI Key InChIKey=GFJJQECNHHNDBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50094555   

TargetProstaglandin G/H synthase 1(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094555(5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...)
Affinity DataIC50: 100nMAssay Description:Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094555(5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...)
Affinity DataIC50: 14.5nMAssay Description:Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50094555(5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...)
Affinity DataIC50: 14.5nMAssay Description:Inhibition of mouse macrophage COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed