BDBM50094500 2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-6-carbonitrile::CHEMBL344602

SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cc3ccc(cc3[nH]2)C#N)CC1

InChI Key InChIKey=QHTTYYWWULUJBN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50094500   

TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094500(2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094500(2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  880nMAssay Description:Binding affinity against Dopamine receptor D1 from bovine striatal membranes using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094500(2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094500(2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094500(2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  3.30E+4nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed