BDBM50093789 CHEMBL541829::Succinic acid mono-(2-dimethylamino-1-{2-[2-(3-methoxy-phenyl)-ethyl]-phenoxymethyl}-ethyl) ester; hydrochloride

SMILES COc1cccc(CCc2ccccc2OCC(CN(C)C)OC(=O)CCC(O)=O)c1

InChI Key InChIKey=FFYNAVGJSYHHFO-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50093789   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Mitsubishi Kasei

Curated by ChEMBL
LigandPNGBDBM50093789(Succinic acid mono-(2-dimethylamino-1-{2-[2-(3-met...)
Affinity DataIC50: 51nMAssay Description:Antagonistic activity against 5-hydroxytryptamine 2 receptor on rat frontal cortex membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Welfide

Curated by ChEMBL
LigandPNGBDBM50093789(Succinic acid mono-(2-dimethylamino-1-{2-[2-(3-met...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was evaluated for the ability to displace [3H]- 8-OH -DPAT from 5-hydroxytryptamine 1A receptor ( striata of male wistar rats)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
LigandPNGBDBM50093789(Succinic acid mono-(2-dimethylamino-1-{2-[2-(3-met...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was evaluated for the ability to displace [3H]prazosin binding to Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Mitsubishi Kasei

Curated by ChEMBL
LigandPNGBDBM50093789(Succinic acid mono-(2-dimethylamino-1-{2-[2-(3-met...)
Affinity DataKi:  7.90nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from striata wistar rats by [3H]ketanserin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Mitsubishi Kasei

Curated by ChEMBL
LigandPNGBDBM50093789(Succinic acid mono-(2-dimethylamino-1-{2-[2-(3-met...)
Affinity DataKi:  18nMAssay Description:Inhibition of 5-hydroxytryptamine 2 induced vasoconstriction of rat caudal artery.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details Article
PubMed