BDBM50093366 2-(4-Amino-phenyl)-1H-benzoimidazole-4-carboxylic acid amide::CHEMBL134197

SMILES NC(=O)c1cccc2nc([nH]c12)-c1ccc(N)cc1

InChI Key InChIKey=CORDOWZJZKLEHO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093366   

TargetPoly [ADP-ribose] polymerase 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50093366(2-(4-Amino-phenyl)-1H-benzoimidazole-4-carboxylic ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PARP1 (unknown origin) assessed as reduction in biotinylated poly(ADP-ribose) incorporation on to histone protein by ELISA based colori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50093366(2-(4-Amino-phenyl)-1H-benzoimidazole-4-carboxylic ...)
Affinity DataKi:  11nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed