BDBM50093341 CHEMBL3586658::US9951014, Name 10c

SMILES CN(CCN)c1cccc(CCc2cc(C)cc(N)n2)c1

InChI Key InChIKey=VBHYLMXKEWJPQR-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50093341   

TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  56nMAssay Description:Inhibition of human recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  56nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  62nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  62nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Northwestern University

US Patent
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  2.90E+3nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent

TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by oxyhemoglobin NO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

US Patent
LigandPNGBDBM50093341(CHEMBL3586658 | US9951014, Name 10c)
Affinity DataKi:  1.07E+4nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
Go to US Patent