BDBM50093095 2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-acetamide::CHEMBL56038

SMILES NC(=O)CN[C@H](COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=MWKJCJFYJWIFLL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50093095   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50093095(2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50: 0.530nMAssay Description:Binding affinity towards human Tachykinin receptor 1 expressed in CHO cells by the displacement of [125 I] substance PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50093095(2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50: 0.525nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50093095(2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed