BDBM50093091 2-[(1R,2R)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butylamino]-acetamide::CHEMBL405129

SMILES NC(=O)CN[C@@H](COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)[C@H](CCN1CCC(O)(CC1)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=OXQZXDGLSIMETJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093091   

TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093091(2-[(1R,2R)-1-(3,5-Bis-trifluoromethyl-benzyloxymet...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50093091(2-[(1R,2R)-1-(3,5-Bis-trifluoromethyl-benzyloxymet...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed