BDBM50093070 CHEMBL3586561

SMILES CO[C@@H]1CC[C@H](CN2C(=O)CNc3ncc(nc23)-c2ccc(nc2C)-c2nc[nH]n2)CC1

InChI Key InChIKey=KVEPKTYZFVUHKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093070   

TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50093070(CHEMBL3586561)
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50093070(CHEMBL3586561)
Affinity DataIC50: 4nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2016
Entry Details Article
PubMed