BDBM50092921 3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-1-morpholin-4-yl-propenone::CHEMBL128805

SMILES Clc1ccc(Sc2ccccc2\C=C\C(=O)N2CCOCC2)c(Cl)c1

InChI Key InChIKey=VMANJRSMYADBHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092921   

LigandPNGBDBM50092921(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-1-morph...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092921(3-[2-(2,4-Dichloro-phenylsulfanyl)-phenyl]-1-morph...)
Affinity DataIC50: 5.30E+3nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed