BDBM50092906 3-{4-[2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-ylmethyl)-phenylsulfanyl]-3-chloro-phenyl}-1-morpholin-4-yl-propenone::CHEMBL262940

SMILES Clc1cc(\C=C\C(=O)N2CCOCC2)ccc1Sc1ccccc1CN1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key InChIKey=PODGAZYUFOSBKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092906   

LigandPNGBDBM50092906(3-{4-[2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1...)
Affinity DataIC50: 100nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092906(3-{4-[2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1...)
Affinity DataIC50: 360nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed