BDBM50092901 3-[4-(2,4-Dichloro-phenylsulfanyl)-3-nitro-phenyl]-N-[3-(2-oxo-pyrrolidin-1-yl)-propyl]-acrylamide::CHEMBL422802

SMILES [O-][N+](=O)c1cc(\C=C\C(=O)NCCCN2CCCC2=O)ccc1Sc1ccc(Cl)cc1Cl

InChI Key InChIKey=JMKWZXFWHSLFSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092901   

LigandPNGBDBM50092901(3-[4-(2,4-Dichloro-phenylsulfanyl)-3-nitro-phenyl]...)
Affinity DataIC50: 170nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092901(3-[4-(2,4-Dichloro-phenylsulfanyl)-3-nitro-phenyl]...)
Affinity DataIC50: 140nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed