BDBM50092900 1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-ethyl-phenylsulfanyl)-3-nitro-phenyl]-propenone::CHEMBL130486

SMILES CCc1ccccc1Sc1ccc(\C=C\C(=O)N2CCN(CC2)C(C)=O)cc1[N+]([O-])=O

InChI Key InChIKey=MDLWTUYIAFVKGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092900   

LigandPNGBDBM50092900(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-ethyl-phenylsu...)
Affinity DataIC50: 65nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092900(1-(4-Acetyl-piperazin-1-yl)-3-[4-(2-ethyl-phenylsu...)
Affinity DataIC50: 100nMAssay Description:Evaluated for its ability to block the adherence of JY-8 cells to immobilized ICAM-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed