BDBM50092887 4-Methyl-2-trifluoromethyl-pyrimidine-5-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide::CHEMBL131007

SMILES Cc1nc(ncc1C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=SGKUTFVUTBIBKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092887   

TargetTranscription factor Jun(Human)
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50092887(4-Methyl-2-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed