BDBM50092826 (2S)-2-amino-5-{[(1R)-1-[({[(4-bromophenyl)(hydroxy)amino]carbonyl}thio)methyl]-2-(carboxyamino)-2-oxoethyl]amino}-5-oxopentanoic acid::(S)-2-amino-5-((R)-3-((4-bromophenyl)hydroxycarbamoylthio)-1-(carboxymethylamino)-1-oxopropan-2-ylamino)-5-oxopentanoic acid::CHEMBL128872::S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione

SMILES N[C@@H](CCC(=O)N[C@@H](CSC(=O)N(O)c1ccc(Br)cc1)C(=O)NCC(O)=O)C(O)=O

InChI Key InChIKey=IQPLOQWSCZRUCA-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50092826   

TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  14nMAssay Description:Binding affinity for Glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  14nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  14nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGlyoxalase I(Baker's yeast)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  1.15E+3nMAssay Description:Inhibition of yeast glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity on yeast glyoxalase I (GlxI) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlyoxalase I(Baker's yeast)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of yeast glyoxalase1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092826(S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione |...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity on Pseudomonas putida glyoxalase I (GlxI) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed