BDBM50092824 CHEMBL131578::S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione

SMILES N[C@@H](CCC(=O)N[C@@H](CSC(=O)N(O)c1ccc(Cl)cc1)C(=O)NCC(O)=O)C(O)=O

InChI Key InChIKey=AJDQQFLYKZABLT-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50092824   

TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  46nMAssay Description:Competitive inhibition of GLO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  46nMAssay Description:Binding affinity for Glyoxalase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human glyoxalase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  46nMAssay Description:Inhibition of human erythrocyte Glyoxalase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHydroxyacylglutathione hydrolase, mitochondrial(Bovine)
Chengdu University

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of bovine liver glyoxalase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity on yeast glyoxalase I (GlxI) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLactoylglutathione lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50092824(S-(N-4chlorophenyl-N-hydroxycarbamoyl)glutathione ...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity on Pseudomonas putida glyoxalase I (GlxI) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed