BDBM50092807 CHEMBL3586411

SMILES [H][C@@]12CCC=C(COC(=O)c3cc(Br)c[nH]3)[C@]1(C)CC[C@H](C)[C@@]2(C)CC\C(C)=C\C[n+]1cn(C)c2ncnc(N)c12

InChI Key InChIKey=ULTNQKUXFQRXIO-UHFFFAOYSA-O

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50092807   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant PTP1B using pNPP as substrate assessed as rate of hydrolysis incubated for 10 mins prior to substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant TCPTP (1 to 317 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant CD45 using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50092807(CHEMBL3586411)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details Article
PubMed