BDBM50092789 CHEMBL3586405

SMILES CC(C)(O)c1ccc(cn1)-c1cnc2[nH]c(=O)n(CCC3CCOCC3)c2n1

InChI Key InChIKey=ONDJQRZDLSDOJA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092789   

TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL

LigandBDBM50092789(CHEMBL3586405)Copy SMILESCopy InChI

Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using GST-p70S6 as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Celgene

Curated by ChEMBL

LigandBDBM50092789(CHEMBL3586405)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL