BDBM50092788 CHEMBL3586381

SMILES CC(C)(O)c1ccc(cn1)-c1cnc2NC(=O)CN(CCC3CCOCC3)c2n1

InChI Key InChIKey=UVDSVTKKZYTBOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092788   

TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50092788(CHEMBL3586381)
Affinity DataIC50: 240nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50092788(CHEMBL3586381)
Affinity DataIC50: 103nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed