BDBM50092778 CHEMBL3586390

SMILES COCCN1CC(=O)Nc2ncc(nc12)-c1ccc(nc1)C(C)(C)O

InChI Key InChIKey=NJPJPESOUGQOMJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092778   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Celgene

Curated by ChEMBL

LigandBDBM50092778(CHEMBL3586390)Copy SMILESCopy InChI

Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL

LigandBDBM50092778(CHEMBL3586390)Copy SMILESCopy InChI

Affinity DataIC50: 436nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL