BDBM50092768 CHEMBL3586403

SMILES CO[C@H]1CC[C@@H](CC1)N1CC(=O)Nc2ncc(nc12)-c1ccc(nc1)C(C)(C)O

InChI Key InChIKey=ZGLONRFJOSBXER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092768   

LigandPNGBDBM50092768(CHEMBL3586403)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50092768(CHEMBL3586403)
Affinity DataIC50: 340nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50092768(CHEMBL3586403)
Affinity DataIC50: 103nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed